Featured Publications

A phase I study of a PARP1-targeted topical fluorophore for the detection of oral cancer (Link)

Paula Demétrio de Souza França, Susanne Kossatz, Christian Brand, et al. 

Validation of the use of a fluorescent PARP1 inhibitor for the detection of oral, oropharyngeal and oesophageal epithelial cancers (Link)

Susanne Kossatz, Giacomo Pirovano, Paula Demétrio de Souza França, et al. 

Nature Biomedical Engineering, 2020, 4, 272–285.

Fluorescence-guided resection of tumors in mouse models of oral cancer (Link)

Paula Demétrio de Souza França, Navjot Guru, Sheryl Roberts, et al. 

Scientific Reports, 2020, 10, 11175.

Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent (Link)

Susanne Kossatz, Christian Brand, Stanley Gutiontov, et al. 

Scientific Reports, 2016, 6, 21371. 


Combined PARP1-targeted nuclear contrast and reflectance contrast enhances confocal microscopic detection of basal cell carcinoma (Link)

Aditi Sahu, Jose Cordero, Xiancheng Wu et al. 

Journal of Nuclear Medicine, 2021, in print

Smartphone epifluorescence microscopy for cellular imaging of fresh tissue in low-resource settings (Link)

Wenbin Zhu, Giacomo Pirovano, Patrick K. O’Neal, et al. 

Biomedical Optics Express, 2020, 11, 89-98.

Poly(ADP-ribose)polymerase1: A potential molecular marker to identify cancer during colposcopy procedures (Link)

Paula Demétrio de Souza França, Navjot Guru, Abigail R. Kostolansky, et al. 

Journal of Nuclear Medicine, 2021, 62, 941-948.

Nanoemulsion-based delivery of fluorescent PARP inhibitors in mouse models of small cell lung cancer (Link)

Junior Gonzales, Susanne Kossatz, Sheryl Roberts, et al. 

Bioconjugate Chem, 2018, 29, 3776–3782.

Brandon Carney, Susanne Kossatz, Thomas Reiner, et al. 

Journal of Nuclear Medicine, 2016, 58, 1025-1030.

Effect of small-molecule modification on single-cell pharmacokinetics of PARP inhibitors (Link)

Brandon Carney, Susanne Kossatz and Thomas Reiner, et al. 

Molecular Cancer Therapeutics, 2014, 13, 986-995.

PARPi-FL - a fluorescent PARP1 inhibitor for glioblastoma imaging (Link)

Christopher P. Irwin, Yasiri Portorreal, Christian Brand, et al. 

Neoplasia, 2014, 5, 432-440.

Single-cell and subcellular pharmacokinetic imaging allows insight into drug action in vivo (Link)

Greg M. Thurber, Katy S. Yang, Thomas Reiner, et al. 

Nature Communications, 2013, 4, 1504.

Imaging therapeutic PARP inhibition in vivo through bioorthogonally developed companion imaging agents (Link)

Thomas Reiner, Jessica Lacy, Edmund J. Keliher, et al. 

Neoplasia, 2012, 14, 169-170.